2025

Schmitz, J., Bartkowiak, A.L., Rose, M., Kolks, N., Petzsch, P., Solanki, V., Stoffel, A., Faßbender, B., Lepping, L., Volkamer, J., Köhrer, K., Seifert, M., Mahmoudi, T., Zuiverloon, TCM., Niegisch, G., Hoffmann, MJ. (2026), Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107. Mol Oncol. https://doi.org/10.1002/1878-0261.70148

Niemann, V., Brack, F., Rolauer, L., Kaczur, J., Petzsch, P., Köhrer, K., Quast, C., Gerdes, N., Bouvain, P., Voigt, K., Krüger, M., Brückner, A., Fleischmann, BK., Wenzel, D., Barnowski, P., Zimmermann, L-M., Simsekyilmaz, S., Filler, T., Ibing, W., Feige, T., Krott, KJ., Wagenhäuser, MU., Fischer, JW., Elvers, M., Sengle, G., Flögel, U., Hundhausen, C., Suvorava, T., Grandoch, M. (2025), Hyaluronan synthase 3 deficiency lowers the incidence of ruptures of abdominal aortic aneurysms by reducing monocyte infiltration. Front. Immunol. 16:1680246. https://doi.org/10.3389/fimmu.2025.1680246

Helle M., Sorg UR., Ptok J., Thomas RE., Pracht K., Petzsch P., de Bruin A., Jäck H., Köhrer K., Degrandi D., Pfeffer K. (2025), Lymphotoxin beta receptor-/- mice display altered B- and T-cell subpopulations in the bone marrow and peritoneal cavity after Toxoplasma gondii infection. Infect Immun93:e00408-25. https://doi.org/10.1128/iai.00408-25

Schloissnig, S., Pani, S., Ebler, J., Hain, C., Tsapalou, V., Söylev, A., Hüther, P., Ashraf, H., Prodanov, T., Asparuhova, M., Magalhães, H., Hops, W., Sotelo-Fonseca, JE., Fitzgerald, T., Santana-Garcia, W., Moreira-Pinhal, R., Hunt, S., Pérez-Llanos, JP., Wollenweber, TE., Sivalingam, S., Wieczorek, D., Cáceres, M., Gilissen, C., Birney, E., Ding, Z., Jensen, JN., Podduturi, N., Stutzki, J., Rodriguez-Martin. B., Rausch, T., Marschall ,T., Korbel, J.O. (2025), Structural variation in 1,019 diverse humans based on long-read sequencing. Nature644, 442–452. https://doi.org/10.1038/s41586-025-09290-7

Maier-Sam, K., Rupp, O., Voss, A., Nemitz, S., Wollenweber, TE., Procida-Kowalski, T., Wilhelm, J., Gruber, AD., & Lierz, M. (2025), Differential expression of host invasion-associated genes by Sarcocystis calchasi in intermediate versus definitive hosts. PLOS ONE 20(6): e0322226. https://doi.org/10.1371/journal.pone.0322226

Bögershausen, N., Cavdarli, B., Nagai, T., Milev, MP., Wolff, A., Mehranfar, M., Schmidt, J., Choudhary, D., Gutiérrez-Gutiérrez, Ó., Cyganek, L., Saint-Dic, D., Zibat, A., Köhrer, K., Wollenweber, TE., Wieczorek, D., Altmüller, J., Borodina, T., Kaçar, D., Haliloğlu, G., Li, Y., Thiel, C., Sacher, M., Knapik, EW., Yigit, G., & Wollnik, B. (2025), SEC24C deficiency causes trafficking and glycosylation abnormalities in an epileptic encephalopathy with cataracts and dyserythropoeisis. JCI Insight. https://doi.org/10.1172/jci.insight.173484

Bahr, J., Poschmann, G., Jungmann, A., Busch, M., Ding, Z., Vogt, J., Zalfen, R., Steinhausen, J., Euan Martínez, AA., Wachtmeister, T., Rickert, D., Lautwein, T., Alter, C., Amrute, JM., Lavine, KJ., Köhrer, K., Levkau, B., Most, P., Stühler, K., Hesse, J., Schrader, J. (2025), A secretome atlas of cardiac fibroblasts from healthy and infarcted mouse hearts. Commun Biol 8, 675. https://doi.org/10.1038/s42003-025-08083-y

Katahira, I., Liebrand, N., Gorzkiewicz, M., Klahm, NP., Abromavičiūtė, D., Werner, J., Krings, KS., Orywol, S., Lautwein, T., Köhrer, K., Herebian, D., Mayatepek, E., Anstötz, M., Bergmann, AK., Kondadi, AK., Xu, HC., Pandyra, AA., Kobayashi, T., Brenner, D., Floss, T., Kalinke, U., Reichert, AS., Lang, PA. (2025), Controlling mitochondrial membrane architecture via MIC60 determines viral replication to promote anti-viral immunity. Cell Rep 44(7), 115922. https://doi.org/10.1016/j.celrep.2025.115922

Kotthoff, M., Skowron, M.A., Bremmer, F., Parmaksiz, F., Kretschmer, P., Stephan, A., Fichtner, A., Lautwein, T., Raba, K., Fuß, J., Köhrer, K., Nettersheim, D. (2025), Induction of SOX17 with stimulation of WNT, TGF-beta, and FGF signaling drives embryonal carcinomas into the yolk-sac tumor lineage resulting in increased cisplatin resistance. Int J Cancer 156(11), 2210–2224. https://doi.org/10.1002/ijc.35385

Jepsen, VH., Hanel, A., Picard, D., Bhave, R., Hasselmann, R., Mehtonen, J., Schliehe-Diecks, J., Kath, CJ., Suppiyar, V., Prasad, Y., Schaal, K., Tu, JW., Rüchel, N., Kameri, E., Qin, N., Wang, H., Zhuang, Z., Wagener, R., Blümel, L., Lautwein, T., Hein, D., Koppstein, D., Kögler, G., Remke, M., Bhatia, S., Heinäniemi, M., Borkhardt, A., Fischer, U. (2025), H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape in preleukemia and B cell acute lymphoblastic leukemia. Hemasphere 9(4), e70116. https://doi.org/10.1002/hem3.70116​